6 days in Miami & Florida Keys Itinerary

Florida’s mecca of fun in the sun, the lively tropical metropolis of Miami is one of the world’s top vacation spots.

Start off your visit on the 20th (Tue): zoom along the surf with a waterskiing or jet-skiing adventure, then appreciate the extensive heritage of Art Deco Historic District, then stroll through South Beach, and finally take a stroll through Lincoln Road. Here are some ideas for day two: see the interesting displays at Vizcaya Museum and Gardens, then have fun at Lock & Load Miami, then examine the collection at Lock & Load Museum, and finally browse the different shops at Bayside Marketplace.

For more things to do, maps, reviews, and tourist information, read Miami trip itinerary planning website.

Philadelphia to Miami is an approximately 5.5-hour flight. You can also drive; or take a bus. Traveling from Philadelphia in April, expect nights in Miami to be much hotter, around 71°F, while days are a bit warmer, around 85°F. Finish your sightseeing early on the 21st (Wed) so you can drive to Islamorada.

Islamorada, long recognized as one of the world's top spots for sport fishing, encompasses six islands in the Florida Keys.

Kick off your visit on the 22nd (Thu): get a new perspective on things with Boat Tours & Water Sports and then indulge your thirst for a good beer at Florida Keys Brewing Company.

To find photos, reviews, maps, and more tourist information, use the Islamorada online journey planner.

Drive from Miami to Islamorada in 2 hours. Alternatively, you can take a shuttle; or take a bus. In April in Islamorada, expect temperatures between 86°F during the day and 75°F at night. Finish your sightseeing early on the 22nd (Thu) so you can drive to Key Largo.

The northernmost island of the Florida Keys, Key Largo provides stunning scenery, a number of watersports opportunities, and plenty of areas to relax on vacation.

Kick off your visit on the 22nd (Thu): identify plant and animal life at Florida Keys Wild Bird Rehabilitation Center.

For traveler tips, photos, reviews, and tourist information, read our Key Largo trip planner.

Key Largo is very close to Islamorada. Traveling from Islamorada in April, Key Largo is slightly colder at night with lows of 69°F. Finish your sightseeing early on the 23rd (Fri) so you can drive to Key West.

Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.

Start off your visit on the 24th (Sat): take a memorable tour with Tours, then identify plant and animal life at Key West Butterfly & Nature Conservatory, then see the interesting displays at The Ernest Hemingway Home and Museum, and finally don't miss a visit to Duval Street.

To find other places to visit, reviews, photos, and tourist information, read Key West online travel route planner.

You can drive from Key Largo to Key West in 2.5 hours. Another option is to take a bus. In April in Key West, expect temperatures between 83°F during the day and 74°F at night. Wrap up your sightseeing on the 25th (Sun) early enough to travel to Miami.

Kick off your visit on the 25th (Sun): tour the pleasant surroundings at South Beach and then browse the different shops at Bayside Marketplace.

For ratings, other places to visit, maps, and other tourist information, use the Miami road trip planning tool.

Getting from Key West to Miami by flight takes about 3 hours. Other options: drive; or take a bus. Finish your sightseeing early on the 25th (Sun) to allow enough time to travel back home.